DHEA is a natural hormone in our bodies. Therefore, using it correctly is totally safe. On the other hand, it may lead to increase androgen levels and it has steroid effects.
It is important to get DHEA therapy under the supervision of your doctor since it may increase the risk of certain DHEA-sensitive cancers such as ovarian, prostate, and breast cancers. If you are at risk of having cancer, your doctor will not recommend DHEA therapy.
Also, DHEA therapy is not recommended for pregnant or breastfeeding women.
In addition, DHEA therapy is not recommended for people who have high cholesterol levels or suffer from any condition affecting the blood supply of the heart such as ischemic heart diseases. DHEA therapy has negative effects on HDL or High-density lipoprotein, which is the good cholesterol.
People who suffer from mood disorders such as mania should not be treated by DHEA therapy since it increases the risk of mania and may worsen certain psychiatric conditions.
Other side effects include oily skin, acne, and hair growth in women.