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CJC-1295/Ipamorelin

CJC-1295_Ipamorelin - HRT

CJC-1295 and Ipamorelin are proteins that help stimulate growth hormone release. Although some studies have shown that they do, please note that they aren’t FDA-approved for medical use and should only be used under a doctor’s strict supervision.

If you want to know more about the peptides’ uses and how they help our bodies, book a consultation with us at Hormone Replacement Therapy LA.

What is CJC-1295/ipamorelin?

CJC-1295 and Ipamorelin are peptides commonly used together to stimulate the release of growth hormone. These peptides work by increasing the concentration of growth hormone, which plays essential roles in cellular growth and metabolism, leading to various benefits.

While CJC-1295 is a synthetic peptide that belongs to the category of Growth Hormone-Releasing Hormone (GHRH) analogs, Ipamorelin is a selective GHRH mimetic. In simple words, GHRH is a hormone produced by the brain’s hypothalamus. This hormone’s main function is to instruct the pituitary gland to release growth hormone, or GH, into the blood.

What we know so far about CJC-1295 peptide is that it mimics the functions of growth hormones, but Ipamorelin doesn’t directly mimic GHRH. In fact, it activates ghrelin receptors to promote the release of growth hormones in a more controlled way than CJC-1295.

How do CJC-1295/ipamorelin peptides work?

CJC-1295

It binds to specific receptors in the pituitary gland, stimulating the release of endogenous growth hormone. Unlike natural GHRH, CJC-1295 has an extended half-life, allowing for sustained stimulation.

Ipamorelin

It specifically targets the pituitary gland’s receptors, promoting growth hormone release.

Its shorter half-life necessitates more frequent dosing.

How it works

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What are the benefits of using CJC-1295/ipamorelin?

CJC-1295

  • Increased Lean Muscle Mass: CJC-1295 stimulates growth hormone production, leading to enhanced muscle growth and protein synthesis.
  • Reduced Body Fat: By promoting fat metabolism, it aids in fat loss.
  • Improved Recovery: Faster recovery after intense workouts.
  • Anti-Aging Effects: Some studies suggest potential anti-aging properties.
  • Extended Half-Life: CJC-1295 has a longer duration of action, allowing sustained benefits.

Ipamorelin

  • Minimal Side Effects: Unlike some other peptides, Ipamorelin has fewer adverse effects.
  • Growth Hormone Stimulation: It boosts growth hormone release without affecting cortisol levels.
  • Better Sleep: Users report improved sleep quality.
  • Enhanced Energy Levels: Increased vitality and stamina

What are the benefits of using CJC-1295_ipamorelin

What is the difference between CJC-1295 and ipamorelin?

CJC-1295

  • Administration Route: Subcutaneous (under the skin) injection.
  • Frequency: Typically, it is injected once or twice a week.
  • Timing: Best administered before bedtime or after exercise.
  • Dosage: Dosage varies based on individual needs and goals. Consult a healthcare professional for personalized recommendations.
  • Injection Site: Common injection sites include the abdomen or thigh.
  • Reconstitution: Mix with bacteriostatic water or sterile saline before use.

Ipamorelin

  • Administration Route: Also via subcutaneous injection.
  • Frequency: Usually 2-3 times daily.
  • Timing: Administered before meals or before bedtime.
  • Dosage: Individualized dosing based on desired effects.
  • Injection Site: Similar to CJC-1295, commonly injected into the abdomen or thigh.
  • Reconstitution: Reconstitute with bacteriostatic water or sterile saline.

Is CJC-1295/ipamorelin legal?

CJC-1295 and Ipamorelin are research chemicals. The FDA has not approved them for human use in the US. However, they are legally available for research purposes and are used “off-label” by doctors.

CJC-1295/ipamorelin effectiveness

  1. A study found that subcutaneous CJC-1295 boosted growth hormone and IGF-I levels when given a certain dose. With multiple doses, this holds the potential as a treatment option. It could be used as a therapeutic agent to help manage health issues related to GH and IGF-I levels [1].
  2. Another study showed that growth-releasing hormones like Ipamorelin and GHRP-6 can increase bone mineral content (BMC) by promoting bone growth and dimensions without affecting bone mineral density in adult female rats [2].
  3. Another study suggested that when animals were given prednisolone (a type of steroid), their bodies broke down proteins faster. Growth hormones or Ipamorelin help slow this breakdown process, which means that GH or Ipamorelin can help treat the side effects of steroids [3].

CJC-1295/ipamorelin Near Me

Hormone Replacement Therapy LA offers the best CJC-1295/ipamorelin near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.

References:

  1. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.
  2. Svensson J, Lall S, Dickson SL, Bengtsson BA, Rømer J, Ahnfelt-Rønne I, Ohlsson C, Jansson JO. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats. J Endocrinol. 2000 Jun;165(3):569-77. doi: 10.1677/joe.0.1650569. PMID: 10828840.
  3. Aagaard NK, Grøfte T, Greisen J, Malmlöf K, Johansen PB, Grønbaek H, Ørskov H, Tygstrup N, Vilstrup H. Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats. Growth Horm IGF Res. 2009 Oct;19(5):426-31. doi: 10.1016/j.ghir.2009.01.001. Epub 2009 Feb 23. PMID: 19231263.

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